Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662388 | 0.73 | CA12 (0.41) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL776889 | 0.65 | DPP4 (0.58) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL775057 | 0.65 | DPP4 (0.58) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL21408619 | 0.65 | DPP4 (0.59) | DPP4KMT2AALDH1A1 | |
| SCHEMBL3192231 | 0.62 | ALDH1A1 (0.48) | CA12CA2CA9DPP4KMT2A | |
| SCHEMBL5236635 | 0.62 | PDCD1 (0.44) | DPP4KMT2AALDH1A1MAPT | |
| SCHEMBL27582158 | 0.62 | TDP1 (0.38) | DPP4KMT2AALDH1A1TDP1 | |
| SCHEMBL11333152 | 0.62 | DPP4 (0.65) | CA12CA1CA2CA9DPP4 | |
| SCHEMBL7414477 | 0.62 | DPP4 (0.59) | DPP4KMT2AALDH1A1LMNAHTR7 | |
| SCHEMBL2208060 | 0.62 | DPP4 (0.54) | CA12CA1CA2CA9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |