Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.55 |
| ▸ | DRD4 | P21917 | 6/20 | 0.55 |
| ▸ | DRD2 | P14416 | 6/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | SCN1A | P35498 | 2/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.55 |
| ▸ | HRH2 | P25021 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687111 | 0.91 | OPRM1 (0.58) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL6661040 | 0.89 | OPRM1 (0.61) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL6665100 | 0.88 | OPRM1 (0.60) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL6667218 | 0.87 | OPRM1 (0.58) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL6663747 | 0.87 | OPRM1 (0.59) | OPRM1DRD4DRD2DRD3ADRA2A | |
| Hydrochloric Acid SCHEMBL6661629 | 0.86 | OPRM1 (0.60) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL6425299 | 0.84 | OPRM1 (0.62) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL7681109 | 0.83 | OPRM1 (0.55) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL6665371 | 0.80 | OPRM1 (0.72) | OPRM1DRD4DRD2DRD3ADRA2A | |
| SCHEMBL7683508 | 0.79 | OPRM1 (0.58) | OPRM1DRD4DRD2DRD3ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097924-B1 | 4-hydroxy-4-phenylpiperidine derivatives having opioid agonist activity and pharmaceuticals containing the same | SSP CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-1097924-A1 | 4-hydroxy-4-phenylpiperidine derivatives having -opioid agonist activity and pharmaceuticals containing the same | SSP Co., Ltd. (JP) | 2001-05-09 | — | — | EP | disclosed |