SCHEMBL6663141

SCHEMBL6663141

CCCCC(CCCC)C(=N)N

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.54
CA1 P00915 4/20 0.54
MAPK1 P28482 1/20 0.44
SPHK2 Q9NRA0 1/20 0.42
SPHK1 Q9NYA1 1/20 0.42
SLC1A2 P43004 2/20 0.42
SLC1A1 P43005 2/20 0.42
SLC1A3 P43003 1/20 0.42
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
DNM1 Q05193 1/20 0.36
FDPS P14324 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1816059 0.95 CA2 (0.50) CA2CA1MAPK1SPHK2SPHK1
SCHEMBL19426824 0.95 CA2 (0.50) CA2CA1MAPK1SPHK2SPHK1
SCHEMBL172807 0.93 CA2 (0.50) CA2CA1MAPK1SPHK2SPHK1
SCHEMBL14300072 0.90 CA2 (0.61) CA2CA1MAPK1SPHK2SPHK1
SCHEMBL21650619 0.90 SPHK1 (0.50) CA2CA1SPHK2SPHK1SLC1A2
SCHEMBL10185828 0.90 SPHK1 (0.50) CA2CA1SPHK2SPHK1SLC1A2
SCHEMBL12527667 0.86 SPHK1 (0.46) CA2CA1SPHK2SPHK1SLC1A2
SCHEMBL12527671 0.86 SPHK1 (0.46) CA2CA1SPHK2SPHK1SLC1A2
SCHEMBL13942872 0.86 SPHK1 (0.46) CA2CA1SPHK2SPHK1SLC1A2
SCHEMBL12960930 0.86 SPHK1 (0.46) CA2CA1SPHK2SPHK1SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104540814-A Cyanoguanidine and its use as antiviral agent ABBVIE INC 2015-04-22 CN claimed
EP-2934563-B1 ANTIMICROBIAL COMPOUNDS, THEIR SYNTHESIS AND APPLICATIONS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENT RESEARCH (IN) 2020-07-08 EP disclosed
WO-2017173302-A2 INHIBITORS OF INTEGRIN ALPHA 5 BETA 1 AND METHODS OF USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-10-05 WO disclosed
CN-104540814-A Cyanoguanidine and its use as antiviral agent ABBVIE INC 2015-04-22 CN disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2004009869-A2 CORROSION-INHIBITING COATING FOR METAL SURFACES UNIVERSITY OF DAYTON (US) 2004-01-29 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed