Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10431395 | 1.00 | THRA (0.52) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL11480869 | 1.00 | THRA (0.52) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL1094888 | 1.00 | THRA (0.52) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL3979284 | 1.00 | THRA (0.52) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL8746881 | 0.97 | THRA (0.52) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL29603582 | 0.94 | THRA (0.53) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL1533967 | 0.91 | HRH1 (0.49) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL1938678 | 0.91 | HRH1 (0.49) | THRATHRBPPARALIPGALOX5 | |
| SCHEMBL10731595 | 0.90 | THRA (0.47) | THRATHRBPPARALIPGALOX5 | |
| Sulfuric Acid SCHEMBL11441986 | 0.89 | THRA (0.57) | THRATHRBPPARALIPGALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448069-A1 | DETERIORATION PREVENTIVE AGENT | Takasago International Corporation (JP) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003041517-A1 | DETERIORATION PREVENTIVE AGENT | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-05-22 | — | — | WO | disclosed |