SCHEMBL6663497

SCHEMBL6663497

C/C=C/CC[C@H]1CC[C@H](c2ccc(C(F)(F)OCCc3ccc(C(F)(F)F)cc3)cc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.37
HTR2C P28335 2/20 0.36
IDO1 P14902 3/20 0.33
SPHK1 Q9NYA1 1/20 0.32
PTGER4 P35408 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
PPARG P37231 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666595 0.97 ALDH1A1 (0.33) MAOBHTR2CSPHK1ALDH1A1LMNA
SCHEMBL6664938 0.94 ALDH1A1 (0.32) MAOBSPHK1ALDH1A1LMNAMAPT
SCHEMBL6667617 0.93 ALDH1A1 (0.40) SPHK1ALDH1A1LMNAMAPT
SCHEMBL6661314 0.93 ESR2 (0.33) SPHK1ALDH1A1LMNAMAPTESR2
SCHEMBL6665820 0.93 ALDH1A1 (0.33) SPHK1ALDH1A1LMNAMAPTESR2
SCHEMBL6664028 0.92 ALDH1A1 (0.30) ALDH1A1LMNAMAPT
SCHEMBL6661222 0.92 ALDH1A1 (0.30) ALDH1A1LMNAMAPT
SCHEMBL6661138 0.91 CYP2C9 (0.31)
SCHEMBL6664960 0.91
SCHEMBL6667966 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed