⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948196 | 0.76 | TSHR (0.34) | — | |
| SCHEMBL11658360 | 0.76 | HPGD (0.30) | — | |
| SCHEMBL6666105 | 0.71 | — | — | |
| SCHEMBL10584352 | 0.66 | — | — | |
| SCHEMBL23070781 | 0.66 | — | — | |
| SCHEMBL8356186 | 0.65 | TSHR (0.42) | — | |
| SCHEMBL132533 | 0.65 | — | — | |
| SCHEMBL10602783 | 0.65 | — | — | |
| SCHEMBL28646722 | 0.65 | — | — | |
| SCHEMBL7519217 | 0.63 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154287-B1 | Oxygen permeable contact lens having a hydrophilic surface and method for producing the same | MENICON CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| EP-0713106-B1 | Oxygen permeable contact lens having a hydrophilic surface and method for producing the same | MENICON CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1154287-A2 | Oxygen permeable contact lens having a hydrophilic surface and method for producing the same | Menicon Co., Ltd. (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-5910518-A | PROTECTIVE COATINGS COMPRISING HYDROPHILICITY RENDERING MATERIAL AND SURFACTANT; GOOD APPEARNCE, WETTABILITY AND DURABILITY | MENICON CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| US-5708050-A | POLYETHERSILOXANES FOR HYDROPHILIC LENSES | MENICON CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0713106-A1 | Oxygen permeable contact lens having a hydrophilic surface and method for producing the same | Menicon Co., Ltd. (JP) | 1996-05-22 | — | — | EP | disclosed |