Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593751 | 0.82 | CDC7 (0.45) | POLBERN1LCKMEN1KMT2A | |
| SCHEMBL6593747 | 0.82 | CDC7 (0.45) | POLBERN1LCKMEN1KMT2A | |
| SCHEMBL6594950 | 0.76 | ERN1 (0.45) | POLBERN1LCKMEN1KMT2A | |
| SCHEMBL6594952 | 0.76 | ERN1 (0.45) | POLBERN1LCKMEN1KMT2A | |
| SCHEMBL6594964 | 0.75 | ERN1 (0.44) | POLBERN1LCKMEN1KMT2A | |
| SCHEMBL6594962 | 0.75 | ERN1 (0.44) | POLBERN1LCKMEN1KMT2A | |
| SCHEMBL6665810 | 0.75 | TNF (0.64) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6665598 | 0.74 | KDM4E (0.39) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6594013 | 0.72 | TNF (0.57) | POLBERN1MEN1KMT2AMAPT | |
| SCHEMBL6594011 | 0.72 | TNF (0.57) | POLBERN1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | claimed |
| WO-2004016271-A1 | PYRIMIDONES AS ANTIVIRAL AGENTS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-02-26 | — | — | WO | disclosed |