Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996303 | 0.86 | ELANE (0.57) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL31322986 | 0.86 | ELANE (0.57) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL18256 | 0.84 | KMT2A (0.54) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL10325206 | 0.84 | KMT2A (0.54) | KMT2AMEN1MAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL7736403 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTTDP1KDM4E | |
| Ammonia Solution, Strong SCHEMBL2067052 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTTDP1KDM4E | |
| Phosphine SCHEMBL9464028 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL8906700 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL295126 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL21633900 | 0.81 | KMT2A (0.51) | KMT2AMEN1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013321-A1 | ESTERASE ESTA (XC4A) OF XANTHOMONAS VESICATORIA | DEGUSSA AG (DE) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003018789-A1 | ESTERASE EST4B1 OBTAINED FROM BACILLUS SUBTILIS | DEGUSSA AG (DE) | 2003-03-06 | — | — | WO | disclosed |