Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35418 | 0.87 | TDP1 (0.31) | ALDH1A1 | |
| SCHEMBL1274035 | 0.78 | TSHR (0.33) | TSHRTHRBALDH1A1 | |
| SCHEMBL94906 | 0.72 | TSHR (0.68) | TSHRTHRBALDH1A1 | |
| SCHEMBL19998240 | 0.71 | TSHR (0.65) | TSHRTHRBALDH1A1 | |
| SCHEMBL3949551 | 0.70 | TSHR (0.66) | TSHRTHRBALDH1A1 | |
| SCHEMBL642807 | 0.69 | TSHR (0.44) | TSHRTHRBALDH1A1 | |
| SCHEMBL11659781 | 0.69 | TSHR (0.53) | TSHRTHRBALDH1A1 | |
| SCHEMBL3078233 | 0.68 | TSHR (0.57) | TSHRTHRBALDH1A1 | |
| SCHEMBL1943351 | 0.68 | TSHR (0.57) | TSHRTHRBALDH1A1 | |
| SCHEMBL964801 | 0.68 | TSHR (0.57) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| US-20210332174-A1 | HYDROGEL COMPOSITIONS | OPHTALMIC COMPAGNIE (FR) | 2021-10-28 | — | — | US | claimed |
| US-8263679-B2 | Prepolymers with dangling polysiloxane-containing polymer chains | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | claimed |
| US-20120046382-A1 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | ALCON INC. (CH) | 2012-02-23 | — | — | US | claimed |
| US-8071658-B2 | Prepolymers with dangling polysiloxane-containing polymer chains | NOVARTIS AG (CH) | 2011-12-06 | — | — | US | claimed |
| JP-2010522265-A | — | — | 2010-07-01 | — | — | JP | claimed |
| EP-2129513-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | Novartis Ag (CH) | 2009-12-09 | — | — | EP | claimed |
| WO-2008116131-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | claimed |
| US-20080231798-A1 | Prepolymers with dangling polysiloxane-containing polymer chains | ALCON INC. (CH) | 2008-09-25 | — | — | US | claimed |
| EP-1560043-B1 | Soft contact lenses | JOHNSON & JOHNSON VISION CARE (US) | 2008-06-18 | — | — | EP | claimed |
| EP-1560043-A1 | Soft contact lenses | Johnson & Johnson Vision Care, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| EP-0940693-B1 | Soft contact lenses | JOHNSON & JOHNSON VISION CARE (US) | 2005-06-22 | — | — | EP | claimed |
| US-5998498-A | SILICONE HYDROGEL | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0940693-A2 | Soft contact lenses | Johnson & Johnson Vision Products, Inc. (US) | 1999-09-08 | — | — | EP | claimed |
| EP-2926967-B1 | SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2025-10-08 | — | — | EP | disclosed |
| US-20250242560-A1 | OPHTHALMIC DEVICES FOR DELIVERY OF HYDROPHOBIC COMFORT AGENTS | ALCON INC (CH) | 2025-07-31 | — | — | US | disclosed |
| US-20220380509-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2022-12-01 | — | — | US | disclosed |
| WO-2001027174-A1 | SOFT CONTACT LENSES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2001-04-19 | — | — | WO | disclosed |
| US-5998498-A | SILICONE HYDROGEL | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0940693-A2 | Soft contact lenses | Johnson & Johnson Vision Products, Inc. (US) | 1999-09-08 | — | — | EP | disclosed |