Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584057 | 0.82 | ALDH1A1 (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL1490337 | 0.81 | THRB (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL10430813 | 0.76 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL4340349 | 0.72 | TSHR (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL2491695 | 0.72 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL10766755 | 0.69 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL14351291 | 0.69 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL10901129 | 0.69 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL986796 | 0.68 | ALDH1A1 (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL5839108 | 0.68 | ALDH1A1 (0.35) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046332-A1 | HYDROGEL BASED ON COPOLYMERS CONTAINING SILICONE | EVONIK ROEHM GMBH (DE) | 2011-02-24 | — | — | US | claimed |
| WO-2009146147-A2 | TARGET-RESPONSIVE HYDROGELS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-12-03 | — | — | WO | claimed |
| US-20110046332-A1 | HYDROGEL BASED ON COPOLYMERS CONTAINING SILICONE | EVONIK ROEHM GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| US-6648733-B2 | Polishing pads and methods relating thereto | RODEL HOLDINGS, INC. | 2003-11-18 | — | — | US | disclosed |
| US-20020077036-A1 | Polishing pads and methods relating thereto | ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. | 2002-06-20 | — | — | US | disclosed |
| US-4987893-A | Conformable bandage and coating material | ROCHAL INDUSTRIES, INC. (US) | 1991-01-29 | — | — | US | disclosed |