Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 12/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662217 | 0.87 | OPRM1 (0.53) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL6663581 | 0.84 | OPRM1 (0.59) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL6661392 | 0.79 | KCNA3 (0.77) | KCNA3CCR1CCR3RAB9ANPSR1 | |
| SCHEMBL6667218 | 0.79 | OPRM1 (0.58) | OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL6662830 | 0.75 | OPRM1 (0.57) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL11601787 | 0.74 | KCNA3 (1.00) | KCNA3CCR1CCR3 | |
| Fetoxylate SCHEMBL1815870 | 0.73 | KCNA3 (0.75) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL6665569 | 0.72 | OPRM1 (0.49) | KCNA3OPRM1CCR1RAB9ANPSR1 | |
| SCHEMBL6661040 | 0.72 | OPRM1 (0.61) | OPRM1CCR1RAB9ANPSR1 | |
| Fetoxylate SCHEMBL124040 | 0.72 | KCNA3 (0.74) | KCNA3OPRM1CCR1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097924-B1 | 4-hydroxy-4-phenylpiperidine derivatives having opioid agonist activity and pharmaceuticals containing the same | SSP CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6362203-B1 | ANALGESICS | SSP CO., LTD (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1097924-A1 | 4-hydroxy-4-phenylpiperidine derivatives having -opioid agonist activity and pharmaceuticals containing the same | SSP Co., Ltd. (JP) | 2001-05-09 | — | — | EP | disclosed |