SCHEMBL6664023

SCHEMBL6664023

Cc1cc2cccc3ccc4c5ccccc5c(C)c1c4c32

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 9/20 0.55
FYN P06241 2/20 0.55
ACHE P22303 2/20 0.55
AHR P35869 2/20 0.55
ERBB2 P04626 1/20 0.55
MAOA P21397 1/20 0.55
ALDH1A1 P00352 6/20 0.50
HPGD P15428 5/20 0.50
HSD17B10 Q99714 5/20 0.50
TSHR P16473 4/20 0.50
CYP3A4 P08684 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
MAPK1 P28482 1/20 0.50
CASP1 P29466 1/20 0.50
RAB9A P51151 1/20 0.50
CASP7 P55210 1/20 0.50
ATM Q13315 1/20 0.50
HIF1A Q16665 1/20 0.50
THRB P10828 1/20 0.50
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27533493 0.82 ALDH1A1 (0.52) CYP1A2FYNACHEAHRERBB2
SCHEMBL31414281 0.82 ALDH1A1 (0.52) CYP1A2FYNACHEAHRERBB2
SCHEMBL28537550 0.81 ALDH1A1 (0.50) CYP1A2FYNACHEAHRERBB2
SCHEMBL598697 0.80 HSD17B10 (0.64) CYP1A2FYNACHEAHRERBB2
SCHEMBL4850561 0.79 CYP1A2 (0.69) CYP1A2FYNACHEAHRERBB2
SCHEMBL23023807 0.78 ALDH1A1 (0.61) CYP1A2FYNACHEAHRERBB2
SCHEMBL11016280 0.78 HPGD (0.47) CYP1A2FYNACHEAHRERBB2
SCHEMBL598673 0.77 CYP1A2 (0.67) CYP1A2FYNACHEAHRERBB2
SCHEMBL531237 0.77 ALDH1A1 (0.64) CYP1A2FYNACHEAHRERBB2
SCHEMBL30822825 0.77 ALDH1A1 (0.64) CYP1A2FYNACHEAHRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040077080-A1 Compositions and methods for induction of proteins involved in xenobiotic metabolism PURACYP 2004-04-22 US disclosed
WO-2004016759-A2 COMPOSITIONS AND METHODS FOR INDUCTION OF PROTEINS INVOLVED IN XENOBIOTIC METABOLISM RAUCY JUDY (US) 2004-02-26 WO disclosed