Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507377 | 0.81 | HSD11B1 (0.39) | CTSCHSD11B1HPGDMAPTCYP2C19 | |
| SCHEMBL10984814 | 0.70 | TAAR1 (0.42) | HPGDMAPTCYP2C19ADRA2AADRA2B | |
| SCHEMBL6657473 | 0.70 | CTSC (0.35) | CTSCHSD11B1HPGDMAPTCYP2C19 | |
| SCHEMBL28708090 | 0.67 | TAAR1 (0.39) | HSD11B1HPGDMAPTCYP2C19ADRA2A | |
| Acetic Acid SCHEMBL29201773 | 0.67 | CYP2C19 (0.44) | HSD11B1HPGDMAPTCYP2C19CYP3A4 | |
| SCHEMBL30960368 | 0.67 | GRIN2B (0.44) | HSD11B1HPGDMAPTCYP2C19ADRA2A | |
| SCHEMBL8285020 | 0.66 | HSD11B1 (0.47) | HSD11B1HPGDMAPTKMT2ANPC1 | |
| SCHEMBL27593899 | 0.64 | HSD11B1 (0.40) | HSD11B1HPGDMAPTCYP2C19TAAR1 | |
| SCHEMBL4021034 | 0.64 | HSD11B1 (0.39) | CTSCHSD11B1HPGDMAPTCYP2C19 | |
| SCHEMBL17033075 | 0.63 | HSD11B1 (0.43) | HSD11B1MAPTCYP2C19ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442033-A1 | OMEGA-CYCLOALKYL 17-HETEROARYL PROSTAGLANDIN E2 ANALOGS AS EP2-RECEPTOR AGONISTS | Allergan, Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-1438104-A1 | CO-CYCLOALKYL 17-HETEROARYL PROSTAGLANDIN E2 ANALOGS AS EP2-RECEPTOR AGONISTS | Allergan, Inc. (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003040126-A1 | φ-CYCLOALKYL 17-HETEROARYL PROSTAGLANDIN E2 ANALOGS AS EP2-RECEPTOR AGONISTS | ALLERGAN, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003037433-A1 | CO-CYCLOALKYL 17-HETEROARYL PROSTAGLANDIN E2 ANALOGS AS EP2-RECEPTOR AGONISTS | ALLERGAN, INC. (US) | 2003-05-08 | — | — | WO | disclosed |