SCHEMBL6664049

SCHEMBL6664049

CCc1ccc(C(F)(F)OCCc2cc(F)c(OC(F)(F)F)c(F)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 4/20 0.35
EDNRB P24530 2/20 0.32
EDNRA P25101 2/20 0.32
FFAR1 O14842 1/20 0.31
KIF11 P52732 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
TSHR P16473 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663201 0.91 TAAR1 (0.30) TAAR1PPARDPPARA
SCHEMBL6661951 0.88 HTR2A (0.36)
SCHEMBL6662997 0.86 KIF11 (0.33) FFAR4EDNRBEDNRAKIF11TAAR1
SCHEMBL6666318 0.86 CACNA1H (0.36) EDNRBEDNRA
SCHEMBL6661336 0.85 FFAR4 (0.34) FFAR4EDNRBEDNRA
SCHEMBL6662044 0.84 DAO (0.35) FFAR4EDNRBEDNRAKIF11TAAR1
SCHEMBL6664131 0.83 KIF11 (0.33) FFAR4EDNRBEDNRAKIF11TAAR1
SCHEMBL7734959 0.83 DAO (0.40) FFAR4TSHRPPARDPPARA
SCHEMBL6664946 0.82 TSHR (0.42) EDNRBEDNRAKIF11TSHRPPARD
SCHEMBL7731008 0.81 TSHR (0.35) TSHRPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed