Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663207 | 0.90 | MEN1 (0.32) | CASR | |
| SCHEMBL6663001 | 0.88 | ALDH1A1 (0.33) | CASRPDE2AALDH1A1LMNA | |
| SCHEMBL6661953 | 0.87 | HTR2A (0.35) | ALDH1A1LMNA | |
| SCHEMBL6661343 | 0.86 | PDE4A (0.30) | — | |
| SCHEMBL6666325 | 0.85 | PDE2A (0.45) | CASRPDE2A | |
| SCHEMBL6662051 | 0.84 | CASR (0.34) | CASRPDE2AALDH1A1LMNA | |
| SCHEMBL6664134 | 0.83 | ALDH1A1 (0.35) | CASRPDE2AALDH1A1LMNA | |
| SCHEMBL6664947 | 0.81 | PDE2A (0.44) | PDE2AEPHX1ALDH1A1 | |
| SCHEMBL6663195 | 0.81 | CYP2A6 (0.34) | — | |
| SCHEMBL7731008 | 0.80 | TSHR (0.35) | PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |