Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664086 | 0.84 | AGTR1 (0.63) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL7020979 | 0.80 | AGTR1 (0.65) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL7095882 | 0.79 | AGTR1 (0.68) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL683804 | 0.77 | AGTR1 (0.66) | AGTR1TBXA2RAGTR2PDE3A | |
| Tasosartan SCHEMBL49626 | 0.77 | AGTR1 (0.71) | AGTR1TBXA2RAGTR2PDE3A | |
| Tasosartan SCHEMBL49627 | 0.77 | AGTR1 (1.00) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL13714544 | 0.77 | AGTR1 (0.68) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL683885 | 0.76 | AGTR1 (0.65) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL7430153 | 0.74 | AGTR1 (0.62) | AGTR1TBXA2RAGTR2PDE3A | |
| SCHEMBL8600068 | 0.72 | AGTR1 (0.54) | AGTR1TBXA2RAGTR2PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981507-B1 | PROCESS FOR THE REMOVAL OF HEAVY METALS | ZAMBON SPA (IT) | 2004-08-18 | — | — | EP | disclosed |
| US-6239301-B1 | USING A CYSTEINE DERIVATIVE | ZAMBON GROUP S.P.A. (IT) | 2001-05-29 | — | — | US | disclosed |