Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664361 | 1.00 | POLB (0.38) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6662590 | 0.99 | POLB (0.39) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6662600 | 0.99 | POLB (0.39) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6663602 | 0.90 | THRB (0.40) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6663605 | 0.90 | THRB (0.40) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6658677 | 0.88 | THRB (0.40) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6658675 | 0.88 | THRB (0.40) | POLBCA2APPKDM4ESMN1; SMN2 | |
| SCHEMBL6662326 | 0.87 | THRB (0.39) | POLBCA2KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6662330 | 0.87 | THRB (0.39) | POLBCA2KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6662716 | 0.86 | POLB (0.38) | POLBAPPKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165721-B1 | LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING | QINETIQ LTD (GB) | 2004-08-04 | — | — | EP | disclosed |
| US-6696110-B1 | THERMOGRAPHY | QINETIQ LIMITED (GB) | 2004-02-24 | — | — | US | disclosed |
| EP-1165721-A2 | LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000060027-A2 | LIQUID CRYSTALLINE ALKENYL COMPOUNDS INCORPORATING AN HETEROCYCLIC FIVE-MEMBERED RING | QINETIQ LIMITED (GB) | 2000-10-12 | — | — | WO | disclosed |