Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.59 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.50 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.50 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403555 | 0.91 | KCNA3 (0.58) | LTA4HPCSK9ORAI1ORAI2ORAI3 | |
| SCHEMBL623764 | 0.81 | CA1 (0.57) | LTA4HNR5A1TP53TSHR | |
| Methyl Alcohol SCHEMBL27471432 | 0.81 | LTA4H (0.80) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| SCHEMBL1331014 | 0.80 | LTA4H (0.87) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Benzene SCHEMBL28132981 | 0.80 | LTA4H (0.87) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| SCHEMBL36192 | 0.80 | LTA4H (0.87) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| SCHEMBL6898318 | 0.79 | NR5A1 (0.58) | LTA4HNR5A1LMNATP53TSHR | |
| SCHEMBL22319104 | 0.78 | LTA4H (0.83) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| SCHEMBL28386097 | 0.78 | LTA4H (0.83) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Phosphine SCHEMBL28317749 | 0.78 | LTA4H (0.83) | LTA4HMLNRNR1I2ESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444981-A1 | INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS | Mikoshiba, Katsuhiko (JP) | 2004-08-11 | — | — | EP | disclosed |