Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | DRD3 | P35462 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667765 | 0.89 | KDM4E (0.60) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL6665831 | 0.88 | ALDH1A1 (0.57) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL7809357 | 0.85 | ALDH1A1 (1.00) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL29388444 | 0.85 | ALDH1A1 (1.00) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL11391733 | 0.84 | ALDH1A1 (0.86) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL15282135 | 0.84 | ALDH1A1 (0.86) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| SCHEMBL5679721 | 0.84 | ALDH1A1 (0.75) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| Pefloxacin SCHEMBL34292 | 0.83 | DRD3 (1.00) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| Pefloxacin SCHEMBL29351730 | 0.83 | DRD3 (1.00) | ALDH1A1DRD3KDM4EMEN1KMT2A | |
| Pefloxacin SCHEMBL28251251 | 0.83 | DRD3 (1.00) | ALDH1A1DRD3KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | claimed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5854227-A | Therapeutic derivatives of diphosphonates | ELIZANOR BIOPHARMACUETICALS, INC. | 1998-12-29 | — | — | US | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |