SCHEMBL6664635

SCHEMBL6664635

CC(=O)CC(=O)NC1(C)CC(C)(C)CC(C)(NC(=O)CC(C)=O)C1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931774 0.77 ALDH1A1 (0.34) GAA
SCHEMBL12152205 0.72 PHF8 (0.45)
SCHEMBL21427834 0.69 CCNE1 (0.32) TDP1
SCHEMBL14285815 0.69 SLC22A6 (0.39) GAA
SCHEMBL3076558 0.65 TSHR (0.34) GAA
SCHEMBL23010954 0.64 EPHX2 (0.49)
SCHEMBL3874714 0.61
SCHEMBL11571847 0.61 EPHX2 (0.59)
SCHEMBL23519766 0.60 HDAC1 (0.40)
SCHEMBL1401066 0.60 MGAM (0.45) TDP1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970137-B9 COATING, ADHESIVE AND SEALANT COMPOSITIONS INT COATINGS LTD (GB) 2004-09-15 EP disclosed
US-6521716-B1 Coating, adhesive and sealant compositions AKZO NOBEL N.V. (NL) 2003-02-18 US disclosed
EP-0970137-B1 COATING, ADHESIVE AND SEALANT COMPOSITIONS INT COATINGS LTD (GB) 2002-06-12 EP disclosed
EP-0970137-A1 COATING, ADHESIVE AND SEALANT COMPOSITIONS International Coatings Limited (GB) 2000-01-12 EP disclosed
WO-1998041561-A1 COATING, ADHESIVE AND SEALANT COMPOSITIONS INTERNATIONAL COATINGS LIMITED (GB) 1998-09-24 WO disclosed