Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29864463 | 1.00 | NAPRT (0.61) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL6222089 | 0.84 | NAPRT (0.68) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL2334559 | 0.83 | MKNK1 (0.56) | CYP1A2CYP3A4 | |
| SCHEMBL29701327 | 0.82 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL794394 | 0.82 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| Hydrochloric Acid SCHEMBL2673018 | 0.80 | NAPRT (0.67) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL4505870 | 0.80 | NAPRT (0.57) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL30690282 | 0.78 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL2339100 | 0.78 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL7326169 | 0.78 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226138-B1 | FAB I INHIBITORS | AFFINIUM PHARM INC (CA) | 2004-12-29 | — | — | EP | disclosed |