Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.66 |
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317874 | 0.79 | TLR8 (0.62) | TLR8IKBKBKMT2AMEN1NPC1 | |
| SCHEMBL16836409 | 0.79 | TLR8 (1.00) | TLR8 | |
| SCHEMBL16486514 | 0.78 | TLR8 (1.00) | TLR8 | |
| SCHEMBL1019128 | 0.78 | TLR8 (0.70) | TLR8IKBKBKMT2AMEN1NPC1 | |
| SCHEMBL317873 | 0.78 | TLR8 (0.60) | TLR8IKBKBKMT2AMEN1NPC1 | |
| SCHEMBL16836327 | 0.77 | TLR8 (0.97) | TLR8 | |
| SCHEMBL4915121 | 0.76 | PDE10A (0.53) | TLR8KMT2AMEN1ALDH1A1KDM4E | |
| Formamide SCHEMBL7622881 | 0.76 | TLR8 (0.40) | TLR8BACE1IKBKBKMT2AMEN1 | |
| SCHEMBL16848237 | 0.76 | TLR8 (1.00) | TLR8BACE1IKBKBALDH1A1KDM4E | |
| SCHEMBL29120967 | 0.76 | HTR3A (0.47) | TLR8IKBKBKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022567-A1 | HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-18 | — | — | WO | disclosed |