SCHEMBL6665073

SCHEMBL6665073

CC=CC1CCC(c2ccc(COC(F)(F)Cc3ccc(C4CCC(C=CC)CC4)cc3)cc2)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 1/20 0.34
ESR2 Q92731 4/20 0.33
ESR1 P03372 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6662820 0.95 ESR2 (0.39) HDAC2ESR2
SCHEMBL6666354 0.94 ESR2 (0.33) HDAC2ESR2ESR1CYP3A4CYP2C9
SCHEMBL6663940 0.94 HDAC2 (0.31) HDAC2ESR2
SCHEMBL6666588 0.94 HDAC2 (0.31) HDAC2ESR2
SCHEMBL6664370 0.94 HTR2C (0.39)
SCHEMBL6666302 0.93 CYP2C9 (0.41) HDAC2ESR2ESR1CYP3A4CYP2C9
SCHEMBL6665442 0.92 CARM1 (0.36)
SCHEMBL6665272 0.91 ESR2 (0.34) HDAC2ESR2ESR1CYP3A4CYP2C9
SCHEMBL6665279 0.91 ESR2 (0.34) HDAC2ESR2ESR1CYP3A4CYP2C9
SCHEMBL6665283 0.91 ESR2 (0.34) HDAC2ESR2ESR1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed