Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.73 |
| ▸ | PPARG | P37231 | 10/20 | 0.73 |
| ▸ | PPARD | Q03181 | 5/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150272 | 0.95 | PPARA (0.71) | PPARAPPARGPPARDTAAR1 | |
| SCHEMBL6150513 | 0.91 | PPARA (0.58) | PPARAPPARGPPARDTAAR1SMN1; SMN2 | |
| SCHEMBL5383202 | 0.85 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5396447 | 0.85 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5387695 | 0.84 | PPARA (0.93) | PPARAPPARGPPARD | |
| SCHEMBL5382863 | 0.84 | PPARA (0.93) | PPARAPPARGPPARD | |
| SCHEMBL4984036 | 0.83 | PTPN1 (0.62) | PPARAPPARGPPARDHPGD | |
| SCHEMBL14501938 | 0.82 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5361860 | 0.82 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5976324 | 0.82 | PPARA (0.63) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |