Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 18/20 | 0.61 |
| ▸ | PPARG | P37231 | 13/20 | 0.61 |
| ▸ | PPARD | Q03181 | 6/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14470660 | 0.92 | PTPN1 (0.67) | PTPN1PPARAPPARGPPARD | |
| SCHEMBL6148812 | 0.89 | PTPN1 (0.68) | PTPN1PPARAPPARGPPARDABCB1 | |
| SCHEMBL5027084 | 0.85 | PTPN1 (0.60) | PTPN1PPARAPPARGPPARD | |
| SCHEMBL5024521 | 0.85 | PTPN1 (0.60) | PTPN1PPARAPPARGPPARD | |
| SCHEMBL5024583 | 0.85 | PTPN1 (0.60) | PTPN1PPARAPPARGPPARD | |
| SCHEMBL6150272 | 0.84 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL3967478 | 0.83 | PTPN1 (0.67) | PTPN1PPARAPPARGPPARDABCB1 | |
| SCHEMBL3967486 | 0.83 | PTPN1 (0.67) | PTPN1PPARAPPARGPPARDABCB1 | |
| SCHEMBL6665339 | 0.83 | PPARA (0.73) | PPARAPPARGPPARDHPGD | |
| SCHEMBL6658193 | 0.83 | PPARA (0.59) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675820-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | AstraZeneca AB (SE) | 2006-07-05 | — | — | EP | claimed |
| US-20060142392-A1 | Process for preparing (2s)-3-(4-{2-[amino]-2-oxoethoxy}phenyl)-2-ethoxypropanoic acid derivatives | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | US | claimed |
| WO-2004113270-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | claimed |
| US-20080114064-A1 | Tri(Hydroxymethyl)Methylamine Salt or an Ethanol Amine Salt of (2S)-2-Ethoxy-3-(4-PHENYL) Propanoic Acid | ASTRAZENECA AB (SE) | 2008-05-15 | — | — | US | disclosed |
| EP-1831151-A1 | TRI (HYDROXYMETHYL) METHYLAMINE SALT OR AN ETHANOL AMINE SALT OF (2S) -2-ETHOXY-3- (4-{2- [HEXYL (2- PHENYLETHYL) AMINO]- 2 -OXOETHOXY} PHENYL) PROPANOIC ACID | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| US-20060194879-A1 | Pharmaceutically useful salts of carboxylic acid derivates | ASTRAZENECA AB (SE) | 2006-08-31 | — | — | US | disclosed |
| US-20060142392-A1 | Process for preparing (2s)-3-(4-{2-[amino]-2-oxoethoxy}phenyl)-2-ethoxypropanoic acid derivatives | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | US | disclosed |
| US-20060142389-A1 | Pharmaceutically useful salts of carboxylic acid derivatives | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | US | disclosed |
| WO-2006065214-A1 | TRI (HYDROXYMETHYL) METHYLAMINE SALT OR AN ETHANOL AMINE SALT OF (2S) -2-ETHOXY-3- (4-{2- [HEXYL (2- PHENYLETHYL) AMINO] - 2 -OXOETHOXY} PHENYL) PROPANOIC ACID | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
| EP-1638920-A1 | PROCESSES FOR PREPARING (2S)-3-(4-{2-[AMINO]-2-OXO ETHOXY}PHENYL)-2-ETHOXYPROPANOIC ACID DERIVATIVES | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| EP-1638921-A1 | PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| EP-1638922-A1 | PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES | AstraZeneca AB (SE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110982-A1 | PROCESSES FOR PREPARING (2S)-3-(4-{2-[AMINO]-2-OXOETHOXY}PHENYL)-2-ETHOXYPROPANOIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004110984-A1 | PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004110985-A1 | PHARMACEUTICALLY USEFUL SALTS OF CARBOXYLIC ACID DERIVATES | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142392-A1 | Process for preparing (2s)-3-(4-{2-[amino]-2-oxoethoxy}phenyl)-2-ethoxypropanoic acid derivatives | GRHPR, CFH, CYP2A13 | PTPN1 4006/4885PPARA 1576/4885PPARG 1640/4885 |
| US-20060142389-A1 | Pharmaceutically useful salts of carboxylic acid derivatives | HCAR2, SLC7A1, HCAR3 | PTPN1 1994/4885PPARA 1102/4885PPARG 3027/4885 |
| US-20060194879-A1 | Pharmaceutically useful salts of carboxylic acid derivates | CA2, CACNA1G, CA6 | PTPN1 2258/4885PPARA 274/4885PPARG 408/4885 |
| US-20080114064-A1 | Tri(Hydroxymethyl)Methylamine Salt or an Ethanol Amine Salt of (2S)-2-Ethoxy-3-(4-PHENYL) Propanoic Acid | PNMT, TET3, TET1 | PTPN1 2283/4885PPARA 1083/4885PPARG 2420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.