Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31470926 | 1.00 | NOTUM (0.66) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL25937249 | 0.84 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL13041449 | 0.83 | NOTUM (0.57) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL25430303 | 0.82 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL30452280 | 0.82 | NOTUM (0.65) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL2997057 | 0.82 | NOTUM (0.65) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL41252 | 0.80 | NOTUM (1.00) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL29506395 | 0.80 | NOTUM (1.00) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL30452423 | 0.79 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1MAPK1 | |
| SCHEMBL3004386 | 0.79 | NOTUM (0.61) | NOTUMTSHRRAB9AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077425-A1 | TRANSAMINASE MUTANT AND USE THEREOF | 凯莱英医药化学（阜新）技术有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2004013252-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | ELAM-T LIMITED (GB) | 2004-02-12 | — | — | WO | disclosed |