Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 4/20 | 0.44 |
| ▸ | CCND1 | P24385 | 4/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25430303 | 0.98 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL5070937 | 0.89 | NOTUM (0.58) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL31470926 | 0.84 | NOTUM (0.66) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL6665481 | 0.84 | NOTUM (0.66) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL2997057 | 0.83 | NOTUM (0.65) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL30452280 | 0.83 | NOTUM (0.65) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL10837613 | 0.83 | NOTUM (0.59) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL17287275 | 0.80 | L3MBTL1 (0.57) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL3397331 | 0.80 | NOTUM (0.56) | NOTUMTSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL10836168 | 0.80 | NOTUM (0.56) | NOTUMTSHRRAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |