SCHEMBL6665513

SCHEMBL6665513

NC(=O)CCC1CN(c2ccc(-c3ccc(N4CCN(C(=O)CCl)CC4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 6/20 0.49
CYP2C19 P33261 2/20 0.47
CYP2C9 P11712 1/20 0.47
MAOA P21397 10/20 0.46
MAOB P27338 2/20 0.46
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6795457 0.91 MAOA (0.53) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6796499 0.90 CALML3 (0.47) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6674786 0.89 CALML3 (0.49) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6642127 0.89 CALML3 (0.49) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6797439 0.89 CYP2C19 (0.49) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6669075 0.89 CALML3 (0.47) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6624388 0.88 CALML3 (0.48) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6669916 0.88 MAOA (0.48) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6793143 0.88 MAOA (0.57) CALML3CYP2C19CYP2C9MAOAMAOB
SCHEMBL6674941 0.88 CALML3 (0.52) CALML3CYP2C19CYP2C9MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1289984-A4 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM CO LTD (KR) 2004-11-24 EP disclosed
EP-1289984-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF Dong A Pharmaceutical Co. Ltd. (KR) 2003-03-12 EP disclosed
WO-2001094342-A1 NOVEL OXAZOLIDINONE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF DONG A PHARM. CO., LTD. (KR) 2001-12-13 WO disclosed