Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503256 | 0.86 | SLC6A2 (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2482088 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL2481485 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL8197222 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL1955758 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL6492089 | 0.83 | KDM4E (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6492100 | 0.83 | KDM4E (0.36) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6498188 | 0.82 | F2 (0.35) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL502170 | 0.81 | CXCR2 (0.31) | — | |
| SCHEMBL6688982 | 0.75 | AKR1C3 (0.31) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |