SCHEMBL6665880

SCHEMBL6665880

CC(=O)c1cccc(COCc2cccc(C(C)=O)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.58
MAOA P21397 4/20 0.56
MRGPRX4 Q96LA9 4/20 0.55
ALDH1A1 P00352 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
TP53 P04637 2/20 0.47
PKM P14618 2/20 0.47
NFKB1 P19838 2/20 0.47
NFKB2 Q00653 2/20 0.47
RELA Q04206 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
RAB9A P51151 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18105802 0.88 MAOB (0.51) MAOBMAOAMRGPRX4ALDH1A1NPSR1
SCHEMBL3149977 0.87 MAOB (0.57) MAOBMAOAMRGPRX4TP53PKM
SCHEMBL18106019 0.85 MAOB (0.49) MAOBMAOAMRGPRX4
SCHEMBL18106016 0.85 MAOB (0.49) MAOBMAOAMRGPRX4
SCHEMBL18105888 0.85 MAOB (0.49) MAOBMAOAMRGPRX4
SCHEMBL18105797 0.85 MAOB (0.49) MAOBMAOAMRGPRX4
SCHEMBL18106017 0.85 MAOB (0.49) MAOBMAOAMRGPRX4
SCHEMBL18105989 0.85 MAOB (0.49) MAOBMAOAMRGPRX4
SCHEMBL7053494 0.85 MAOB (0.55) MAOBMAOAMRGPRX4
SCHEMBL6667400 0.85 MAOB (0.55) MAOBMAOAMRGPRX4ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed