SCHEMBL7053494

SCHEMBL7053494

CC(=O)c1cccc(CON)c1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.55
IDO1 P14902 10/20 0.55
MAOA P21397 1/20 0.54
MRGPRX4 Q96LA9 1/20 0.52
AGXT P21549 7/20 0.51
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6665880 0.85 MAOB (0.58) MAOBMAOAMRGPRX4
SCHEMBL3149977 0.84 MAOB (0.57) MAOBMAOAMRGPRX4
SCHEMBL17349941 0.84 FOLH1 (0.59) MRGPRX4
SCHEMBL30331845 0.84 FOLH1 (0.59) MRGPRX4
SCHEMBL1715330 0.83 LOXL2 (0.71) IDO1MRGPRX4AGXT
Hydrochloric Acid SCHEMBL27668461 0.82 FOLH1 (0.58) MRGPRX4
SCHEMBL7053491 0.82 MAOB (0.55) MAOBMAOAMRGPRX4CYP3A4
SCHEMBL6667400 0.82 MAOB (0.55) MAOBMAOAMRGPRX4
Hydrochloric Acid SCHEMBL1715819 0.81 LOXL2 (0.69) IDO1MRGPRX4AGXT
SCHEMBL13513257 0.79 MAOB (0.51) MAOBMAOAMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117751114-A Small molecule modulators of glucocerebrosidase activity and uses thereof 凡况生化公司 2024-03-22 CN disclosed
CN-117642404-A Small molecule modulators of glucocerebrosidase activity and uses thereof 凡况生化公司 2024-03-01 CN disclosed
EP-0882715-B1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA CHEMICAL IND CO LTD (JP) 2003-04-23 EP disclosed
US-6339045-B1 CAN BE USED IN A SMALL AMOUNT, SHOWING A GOOD SELECTIVITY BETWEEN CROP AND WEED, AND CAUSING NO PHYTOTOXICITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-01-15 US disclosed
EP-0882715-A1 NOVEL N-(UNSUBSTITUTED OR SUBSTITUTED)-4-SUBSTITUTED-6-(UNSUBSTITUTED OR SUBSTITUTED)PHENOXY-2-PYRIDINECARBOXAMIDES OR THIOCARBOXAMIDES, PROCESSES FOR PRODUCING THE SAME, AND HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-12-09 EP disclosed