SCHEMBL6665902

SCHEMBL6665902

O=C(OCc1ccccc1)c1ccc(C(=O)OCc2ccccc2)c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
TDP1 Q9NUW8 4/20 0.66
KMT2A Q03164 2/20 0.63
SLC6A2 P23975 1/20 0.63
SLC6A3 Q01959 1/20 0.63
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 5/20 0.57
TSHR P16473 3/20 0.57
MAPK1 P28482 2/20 0.57
CYP3A4 P08684 2/20 0.57
POLB P06746 1/20 0.55
CASP3 P42574 1/20 0.55
RAB9A P51151 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55
SENP6 Q9GZR1 1/20 0.55
EGLN1 Q9GZT9 1/20 0.52
MMP2 P08253 2/20 0.50
MMP9 P14780 2/20 0.50
MMP12 P39900 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27844980 0.90 ALDH1A1 (0.57) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL21012818 0.90 ALDH1A1 (0.57) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL9808151 0.89 ALDH1A1 (0.55) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL3048365 0.86 ALDH1A1 (0.65) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL29388715 0.86 ALDH1A1 (0.89) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL50441 0.86 ALDH1A1 (0.89) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL19669288 0.85 TDP1 (0.71) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL27891487 0.84 ALDH1A1 (0.58) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL2588443 0.84 ALDH1A1 (0.72) ALDH1A1TDP1KMT2ASLC6A2SLC6A3
SCHEMBL28035420 0.84 ALDH1A1 (0.50) ALDH1A1TDP1KMT2ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed