Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661253 | 0.91 | TRPV4 (0.40) | ALDH1A1NPC1HPGDCASP3RAB9A | |
| SCHEMBL6662936 | 0.88 | HSD17B10 (0.41) | HSD17B10TSHRALDH1A1NPC1HPGD | |
| SCHEMBL6665025 | 0.87 | TRPV4 (0.41) | HPGDTRPV4CYP3A4DAORORC | |
| SCHEMBL6663951 | 0.84 | ESR1 (0.42) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL6662869 | 0.83 | ESR1 (0.41) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL9240972 | 0.83 | HSD17B10 (0.49) | HSD17B10TSHRALDH1A1NPC1HPGD | |
| SCHEMBL6666752 | 0.82 | HSD17B10 (0.58) | HSD17B10TSHRALDH1A1NPC1HPGD | |
| SCHEMBL6662961 | 0.81 | ESR1 (0.50) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL6666308 | 0.81 | ESR1 (0.40) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL6661197 | 0.81 | ESR1 (0.40) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |