Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 20/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.60 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666352 | 0.91 | FDPS (0.63) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL6668154 | 0.91 | FDPS (0.63) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL6669214 | 0.84 | FDPS (0.56) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL15452862 | 0.84 | FDPS (0.76) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL9313278 | 0.81 | FDPS (0.77) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL9313105 | 0.79 | FDPS (0.74) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL24616673 | 0.78 | FDPS (0.68) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL10705729 | 0.77 | FDPS (0.62) | FDPSPDE3AGGPS1LMNAADRB3 | |
| SCHEMBL11066276 | 0.76 | FDPS (0.35) | FDPSPDE3AGGPS1LMNAADRB3 | |
| Alendronic Acid SCHEMBL6270347 | 0.75 | FDPS (1.00) | FDPSPDE3AGGPS1LMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831845-B1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS IN (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5854227-A | Therapeutic derivatives of diphosphonates | ELIZANOR BIOPHARMACUETICALS, INC. | 1998-12-29 | — | — | US | disclosed |
| WO-1996040156-A1 | DIPHOSPHONATE DERIVATIVES OF THERAPEUTIC AGENTS | ELIZANOR BIOPHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |