SCHEMBL6666366

SCHEMBL6666366

Cc1cccc(COC(=O)C2CCCC(C(=O)OCc3cccc(C)c3)C2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.47
POLB P06746 2/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
GRIN2B Q13224 1/20 0.44
IDO1 P14902 2/20 0.44
MAOB P27338 2/20 0.44
TSHR P16473 1/20 0.43
NPC1 O15118 1/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667162 0.90 KDM4E (0.52) GAAPOLBMMP2MMP9MMP12
SCHEMBL15709940 0.82 TSHR (0.56) GAATSHRNPC1KMT2AALDH1A1
SCHEMBL15743128 0.82 TSHR (0.56) GAATSHRNPC1KMT2AALDH1A1
SCHEMBL15709938 0.82 TSHR (0.56) GAATSHRNPC1KMT2AALDH1A1
SCHEMBL3215611 0.79 TSHR (0.53) GAAPOLBTSHRNPC1NPSR1
SCHEMBL3210309 0.79 TSHR (0.53) GAAPOLBTSHRNPC1NPSR1
SCHEMBL3210313 0.79 TSHR (0.53) GAAPOLBTSHRNPC1NPSR1
SCHEMBL24358776 0.78 SMN1; SMN2 (0.54) GAATSHRNPC1ALDH1A1
SCHEMBL3209621 0.78 SMN1; SMN2 (0.54) GAATSHRNPC1ALDH1A1
SCHEMBL3208026 0.78 SMN1; SMN2 (0.54) GAATSHRNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed