Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666366 | 0.90 | GAA (0.47) | KDM4EALDH1A1NPC1POLBMMP2 | |
| SCHEMBL31518983 | 0.82 | POLB (0.53) | KDM4EALDH1A1NPC1POLBGAA | |
| SCHEMBL28572234 | 0.82 | ALDH1A1 (0.59) | KDM4EALDH1A1NPC1POLBMMP2 | |
| SCHEMBL31518977 | 0.82 | FABP7 (0.54) | ALDH1A1NPC1 | |
| SCHEMBL522278 | 0.82 | FABP7 (0.54) | ALDH1A1NPC1 | |
| SCHEMBL28672943 | 0.81 | KDM4E (0.55) | KDM4EALDH1A1POLBMMP2MMP9 | |
| SCHEMBL2703515 | 0.80 | FABP7 (0.55) | ALDH1A1NPC1GAA | |
| SCHEMBL21733296 | 0.80 | EPHX1 (0.61) | ALDH1A1NPC1GAA | |
| SCHEMBL5220053 | 0.78 | KDM4E (0.55) | KDM4EALDH1A1MMP2MMP9MMP12 | |
| SCHEMBL20738301 | 0.78 | SMN1; SMN2 (0.47) | KDM4EALDH1A1NPC1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1004621-B1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN CHEMICALS LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6485657-B1 | Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer | TEIJIN, LIMITED (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1004621-A1 | GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2000-05-31 | — | — | EP | disclosed |