Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.60 |
| ▸ | HTR2B | P41595 | 18/20 | 0.60 |
| ▸ | HTR2A | P28223 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362236 | 0.86 | HTR2C (0.66) | HTR2CHTR2BHTR2ANPC1RAB9A | |
| SCHEMBL18854136 | 0.76 | RAB9A (0.55) | NPC1RAB9AKMT2A | |
| SCHEMBL6312109 | 0.75 | HTR2C (0.77) | HTR2CHTR2BHTR2ANPC1RAB9A | |
| SCHEMBL5362705 | 0.73 | HTR2C (0.60) | HTR2CHTR2BHTR2ANPC1RAB9A | |
| SCHEMBL25668464 | 0.71 | RAB9A (0.62) | NPC1RAB9AKMT2A | |
| SCHEMBL5368909 | 0.71 | HTR2C (0.73) | HTR2CHTR2BHTR2ANPC1RAB9A | |
| SCHEMBL6304067 | 0.70 | HTR2C (0.76) | HTR2CHTR2BHTR2ANPC1RAB9A | |
| SCHEMBL6304598 | 0.70 | HTR2C (0.78) | HTR2CHTR2BHTR2ANPC1RAB9A | |
| SCHEMBL1960679 | 0.69 | TRPV1 (0.58) | HTR2CNPC1RAB9AKMT2A | |
| SCHEMBL6305416 | 0.69 | HTR2C (0.55) | HTR2CHTR2BHTR2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485386-A2 | PYRIDINYLOXY DERIVATIVES AS 5-HT RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003076426-A2 | PYRIDINYLOXY DERIVATIVES AS 5-HT RECEPTOR LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-18 | — | — | WO | claimed |