Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 4/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6644781 | 0.89 | CACNA1F (0.49) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL30119801 | 0.88 | GNRHR (0.48) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL6668946 | 0.87 | GNRHR (0.51) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL6669734 | 0.79 | GNRHR (0.58) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL16254117 | 0.78 | GNRHR (0.57) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL6668512 | 0.78 | GNRHR (0.67) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL24709370 | 0.77 | GNRHR (0.49) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL30078679 | 0.77 | GNRHR (0.65) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL6667142 | 0.77 | GNRHR (0.68) | GNRHRCACNA1FCHRM4ADORA3CHRM1 | |
| SCHEMBL17549865 | 0.76 | GNRHR (0.67) | GNRHRCACNA1FCHRM4ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058895-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2016-03-03 | — | — | US | disclosed |
| US-20160058895-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2016-03-03 | — | — | US | disclosed |
| WO-2014184682-A9 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2015-01-29 | — | — | WO | disclosed |
| WO-2014184682-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | OSLO UNIVERSITETSSYKEHUS HF (NO) | 2014-11-20 | — | — | WO | disclosed |
| EP-1401427-A4 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMA (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1401427-A2 | NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | Agouron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002098363-A2 | NON-PEPTIDE GnRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM | AGOURON PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058895-A1 | RADIOLABELED GNRH ANTAGONISTS AS PET IMAGING AGENTS | GNRHR, FSHR, GHRHR | GNRHR 1/4885CACNA1F 2159/4885CHRM4 2314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.