SCHEMBL6667060

SCHEMBL6667060

CCCCCC=CC=CCCCCCCCC1(C(=O)O)OO1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.56
FAAH O00519 4/20 0.48
KDM4E B2RXH2 1/20 0.48
TERT O14746 3/20 0.46
PTPN1 P18031 3/20 0.46
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
MAPT P10636 2/20 0.46
BLM P54132 2/20 0.46
HSD17B10 Q99714 2/20 0.46
FABP4 P15090 2/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALOX15 P16050 1/20 0.46
APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3489435 0.87 PPARG (0.50) FAAHKDM4ETERTPTPN1PPARG
SCHEMBL8873142 0.86 GPR84 (0.43) PTPN1PPARGPPARDPPARAHSD17B10
SCHEMBL9828667 0.76 FASN (0.54) FASNFAAHKDM4ETERTPTPN1
SCHEMBL17192414 0.72 FASN (0.92) FASNFAAHKDM4ETERTPTPN1
SCHEMBL23067684 0.72 PTPN1 (0.67) FASNFAAHKDM4ETERTPTPN1
SCHEMBL23698116 0.72 PTPN1 (0.67) FASNFAAHKDM4ETERTPTPN1
SCHEMBL20514850 0.72 FASN (1.00) FASNFAAHKDM4ETERTPTPN1
SCHEMBL20942832 0.72 PTPN1 (0.67) FASNFAAHKDM4ETERTPTPN1
SCHEMBL21294386 0.72 FASN (0.85) FASNFAAHKDM4ETERTPTPN1
SCHEMBL3793137 0.72 PTPN1 (0.67) FASNFAAHKDM4ETERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004007732-A1 CLONING AND CHARACTERIZATION OF A LIPOXYGENASE FROM PHAEODACTYLUM TRICORNUTUM BASF PLANT SCIENCE GMBH (DE) 2004-01-22 WO disclosed