Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806327 | 0.92 | EIF2AK3 (0.41) | RIPK1EIF2AK3MAPTKMT2AKDM4E | |
| SCHEMBL6665768 | 0.91 | MAPT (0.41) | RIPK1EIF2AK3MAPTKMT2AKDM4E | |
| SCHEMBL6666848 | 0.89 | TP53 (0.39) | RIPK1EIF2AK3MAPTKMT2AMEN1 | |
| SCHEMBL6668213 | 0.89 | AVPR2 (0.42) | RIPK1EIF2AK3MAPTKDM4EALDH1A1 | |
| SCHEMBL6662998 | 0.88 | EIF2AK3 (0.42) | RIPK1EIF2AK3MAPTKMT2AKDM4E | |
| SCHEMBL6666513 | 0.88 | MTTP (0.40) | RIPK1EIF2AK3MAPTHTR2AHTR2C | |
| SCHEMBL6804990 | 0.86 | MAPT (0.44) | RIPK1EIF2AK3MAPTCREBBPNPC1 | |
| SCHEMBL6668674 | 0.86 | EIF2AK3 (0.46) | EIF2AK3MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6664419 | 0.84 | HTR2A (0.41) | RIPK1EIF2AK3MAPTHTR2AHTR2C | |
| SCHEMBL6803618 | 0.84 | RIPK1 (0.40) | RIPK1EIF2AK3MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |