SCHEMBL6667524

SCHEMBL6667524

CCOC(=O)c1ccc(COC(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.64
SMN1; SMN2 Q16637 1/20 0.54
KMT2A Q03164 3/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
MEN1 O00255 1/20 0.53
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
LMNA P02545 1/20 0.53
HTT P42858 2/20 0.52
RAB9A P51151 2/20 0.51
NPC1 O15118 1/20 0.51
ADRB2 P07550 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30684671 0.89 CA12 (0.59) MAPTSMN1; SMN2KMT2ACA12CA1
SCHEMBL571295 0.89 CA12 (0.59) MAPTSMN1; SMN2KMT2ACA12CA1
Hydrochloric Acid SCHEMBL27804731 0.88 CA12 (0.57) MAPTSMN1; SMN2KMT2ACA12CA1
Hydrochloric Acid SCHEMBL27783226 0.88 CA12 (0.57) MAPTSMN1; SMN2KMT2ACA12CA1
SCHEMBL2706461 0.86 KMT2A (0.66) MAPTSMN1; SMN2KMT2ASLC6A2SLC6A3
SCHEMBL2761208 0.85 CA12 (0.57) MAPTSMN1; SMN2KMT2ACA12CA1
SCHEMBL6002245 0.83 KMT2A (0.70) MAPTSMN1; SMN2KMT2ASLC6A2SLC6A3
SCHEMBL11408485 0.83 KMT2A (0.76) MAPTSMN1; SMN2KMT2ACA12CA1
SCHEMBL707407 0.83 CA12 (0.67) MAPTSMN1; SMN2KMT2ACA12CA1
SCHEMBL16691834 0.82 CA12 (0.57) MAPTSMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004621-B1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN CHEMICALS LTD (JP) 2004-09-15 EP disclosed
US-6485657-B1 Gamma-ray stabilizer and thermoplastic polymer compound including the said stabilizer TEIJIN, LIMITED (JP) 2002-11-26 US disclosed
EP-1004621-A1 GAMMA-RAY STABILIZER AND THERMOPLASTIC POLYMER COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 2000-05-31 EP disclosed