SCHEMBL30684671

SCHEMBL30684671

CCOC(=O)c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA7 P43166 3/20 0.59
CA9 Q16790 3/20 0.59
CA14 Q9ULX7 3/20 0.59
HRH3 Q9Y5N1 2/20 0.57
ADRB2 P07550 1/20 0.56
ADRB1 P08588 1/20 0.56
ADRB3 P13945 1/20 0.56
RAB9A P51151 4/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 3/20 0.55
ALDH1A1 P00352 3/20 0.55
KMT2A Q03164 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
KDM4E B2RXH2 2/20 0.55
HCRTR1 O43613 1/20 0.55
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571295 1.00 CA12 (0.59) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL27783226 0.98 CA12 (0.57) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL27804731 0.98 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL2761208 0.95 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL707407 0.93 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL1960994 0.91 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL6667524 0.89 MAPT (0.64) CA12CA1CA2CA7CA9
SCHEMBL9979785 0.89 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL7452434 0.87 MEN1 (0.55) CA12CA1CA2CA7CA9
SCHEMBL7642823 0.86 HRH3 (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110278711-B Tricyclosulfones as rory modulators 百时美施贵宝公司 2023-12-15 CN disclosed