SCHEMBL6667590

SCHEMBL6667590

CCCCCCCCc1ccc(C(F)(F)OC(C)c2ccc(OC(F)(F)F)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.41
HTR2A P28223 2/20 0.39
PDE2A O00408 1/20 0.39
STS P08842 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
CYP3A4 P08684 2/20 0.36
THRB P10828 2/20 0.36
THRA P10827 1/20 0.36
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLCO1B3 Q9NPD5 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667383 1.00 FAAH (0.41) FAAHHTR2APDE2ASTSHDAC3
SCHEMBL6662969 1.00 FAAH (0.41) FAAHHTR2APDE2ASTSHDAC3
SCHEMBL6664177 1.00 FAAH (0.41) FAAHHTR2APDE2ASTSHDAC3
SCHEMBL6666331 1.00 FAAH (0.41) FAAHHTR2APDE2ASTSHDAC3
SCHEMBL6663838 0.99 PDE2A (0.39) FAAHHTR2APDE2ASTSHDAC3
SCHEMBL6666707 0.90 PDE2A (0.42) PDE2AHDAC3HDAC1HDAC2ALDH1A1
SCHEMBL6662955 0.90 HTR2A (0.42) FAAHHTR2AALDH1A1LMNACYP3A4
SCHEMBL6666975 0.89 FAAH (0.43) FAAHHTR2AALDH1A1LMNACYP3A4
SCHEMBL6662750 0.87 HTR2A (0.40) FAAHHTR2AALDH1A1LMNACYP3A4
SCHEMBL6661968 0.87 HTR2A (0.40) FAAHHTR2AALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed