Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 2/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639080 | 0.80 | DAO (0.61) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL9163258 | 0.75 | CYP1A2 (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL30199901 | 0.75 | GAA (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL10070259 | 0.75 | CYP1A2 (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL18995263 | 0.75 | CYP1A2 (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL7938807 | 0.75 | CYP1A2 (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL4741376 | 0.75 | GAA (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL7815453 | 0.75 | CYP1A2 (0.60) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| SCHEMBL527043 | 0.75 | CYP1A2 (1.00) | GAACYP1A2KDM4EHPGDALDH1A1 | |
| Transtorine SCHEMBL5144405 | 0.75 | KDM4E (1.00) | GAACYP1A2KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062001-B1 | ACYL QUINOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1987-05-27 | — | — | EP | claimed |
| EP-3950687-B1 | INDUSTRIAL METHOD FOR SYNTHESISING IMIQUIMOD FROM QUINOLINE-2,4-DIOL APPLICABLE TO THE PHARMACEUTICAL USE THEREOF | GENERYZE (FR) | 2026-01-28 | — | — | EP | disclosed |
| EP-3950687-A1 | INDUSTRIAL METHOD FOR SYNTHESISING IMIQUIMOD FROM QUINOLINE-2,4-DIOL APPLICABLE TO THE PHARMACEUTICAL USE THEREOF | PHV Pharma (FR) | 2022-02-09 | — | — | EP | disclosed |
| EP-2997382-B1 | ALKYL QUINOLONES AS BIOMARKERS OF PSEUDOMONAS AERUGINOSA INFECTION AND USES THEREOF | UNIV NOTTINGHAM (GB) | 2018-07-11 | — | — | EP | disclosed |
| US-20160131648-A1 | ALKYL QUINOLONES AS BIOMARKERS OF PSEUDOMONAS AERUGINOSA INFECTION AND USES THEREOF | THE UNIVERSITY OF NOTTINGHAM (GB) | 2016-05-12 | — | — | US | disclosed |
| US-20160131648-A1 | ALKYL QUINOLONES AS BIOMARKERS OF PSEUDOMONAS AERUGINOSA INFECTION AND USES THEREOF | THE UNIVERSITY OF NOTTINGHAM (GB) | 2016-05-12 | — | — | US | disclosed |
| WO-2014184535-A1 | ALKYL QUINOLONES AS BIOMARKERS OF PSEUDOMONAS AERUGINOSA INFECTION AND USES THEREOF | THE UNIVERSITY OF NOTTINGHAM (GB) | 2014-11-20 | — | — | WO | disclosed |
| EP-1450802-A2 | METHODS FOR THE PREVENTION OR TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003037259-A2 | METHODS FOR THE PREVENTION OR TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2003-05-08 | — | — | WO | disclosed |
| WO-2000074667-A2 | COMPOSITIONS ACTIVE IN TELOMERE DAMAGE COMPRISING A TAXANE AND TELOMERASE INHIBITOR | AU JESSIE L S (US) | 2000-12-14 | — | — | WO | disclosed |
| US-5312922-A | Quinoline derivatives with hydroxy, trifluoromethyl, carboxy and/or bromo substituents | NORDION INTERNATIONAL INC. (CA) | 1994-05-17 | — | — | US | disclosed |
| US-4476132-A | Acylquinolinone derivatives, and antiallergic preparations and methods of inhibiting allergic reactions using them | CIBA-GEIGY CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |
| EP-0062001-A2 | Acyl quinolinone derivatives, processes for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160131648-A1 | ALKYL QUINOLONES AS BIOMARKERS OF PSEUDOMONAS AERUGINOSA INFECTION AND USES THEREOF | NQO2, QARS1, CD14 | GAA 1539/4885CYP1A2 353/4885KDM4E 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.