Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666681 | 0.95 | SPHK1 (0.39) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6663430 | 0.92 | ESR2 (0.42) | ESR2SPHK1SPHK2SIGMAR1HTR2C | |
| SCHEMBL6665221 | 0.92 | ALDH1A1 (0.43) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6664002 | 0.92 | ALDH1A1 (0.43) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6663325 | 0.90 | ALDH1A1 (0.44) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6666928 | 0.90 | ALDH1A1 (0.44) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6664248 | 0.89 | SPHK1 (0.43) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6662832 | 0.89 | SPHK1 (0.43) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6666558 | 0.88 | SPHK1 (0.45) | ESR2SPHK1ALDH1A1LMNAMAPT | |
| SCHEMBL6667712 | 0.87 | SPHK1 (0.44) | SPHK1ALDH1A1LMNAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |