Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200398 | 0.89 | EGLN1 (0.44) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6197114 | 0.89 | EGLN1 (0.44) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6198112 | 0.89 | EGLN1 (0.47) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6198881 | 0.89 | EGLN1 (0.47) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6199436 | 0.88 | EGLN1 (0.44) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6200315 | 0.88 | EGLN1 (0.44) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6201231 | 0.88 | EGLN1 (0.44) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6201585 | 0.87 | EGLN1 (0.43) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6201167 | 0.87 | EGLN1 (0.43) | EGLN1LMNANR3C1PPARGGSK3B | |
| SCHEMBL6201772 | 0.87 | LMNA (0.43) | EGLN1LMNANR3C1PPARGGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |