SCHEMBL6668264

SCHEMBL6668264

CC(C)N(Cc1ccncc1)C(=O)Cc1c(-c2ccccc2)[nH]c2ncccc12

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.78
FNTB P49356 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671324 0.88 FNTA (1.00) FNTAFNTB
SCHEMBL6668193 0.84 FNTA (0.85) FNTAFNTB
SCHEMBL6669170 0.83 FNTA (0.92) FNTAFNTB
SCHEMBL6668130 0.83 FNTA (0.76) FNTAFNTB
SCHEMBL6672695 0.82 FNTA (0.81) FNTAFNTB
SCHEMBL6669026 0.82 FNTA (0.81) FNTAFNTB
SCHEMBL6669322 0.81 FNTA (1.00) FNTAFNTB
SCHEMBL6668429 0.80 FNTA (0.78) FNTAFNTB
SCHEMBL6666624 0.80 FNTA (0.90) FNTAFNTB
SCHEMBL6667023 0.80 FNTA (1.00) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1324985-A4 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 2004-10-06 EP claimed
EP-1324985-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 2003-07-09 EP claimed
WO-2002028831-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2002-04-11 WO claimed
EP-1324985-A4 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 2004-10-06 EP disclosed
EP-1324985-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE Merck & Co., Inc. (US) 2003-07-09 EP disclosed
WO-2002028831-A1 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2002-04-11 WO disclosed