Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 15/20 | 0.58 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668270 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL7117336 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL6668388 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL6668660 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL6668231 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL6668393 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL7129714 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL7123215 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL6668659 | 1.00 | DPP4 (0.58) | DPP4DPP7PREPKCNH2 | |
| SCHEMBL7124849 | 0.98 | DPP4 (0.57) | DPP4DPP7PREPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270562-B1 | Cyclic alpha-amino-gamma-hydroxy-amides, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2004-09-22 | — | — | EP | claimed |
| US-6593312-B2 | Hypoglycemic agents; antidiabetic agents; dietetics | LES LABORATOIRES SERVIER (FR) | 2003-07-15 | — | — | US | claimed |
| US-20030004138-A1 | Cyclic a-amino-y hydroxyamide compounds | LES LABORATOIRES SERVIER (FR) | 2003-01-02 | — | — | US | claimed |
| EP-1270562-A2 | Cyclic alpha-amino-gamma-hydroxy-amides, process for their preparation and pharmaceutical compositions thereof | Les Laboratoires Servier (FR) | 2003-01-02 | — | — | EP | claimed |
| EP-1270562-B1 | Cyclic alpha-amino-gamma-hydroxy-amides, process for their preparation and pharmaceutical compositions thereof | SERVIER LAB (FR) | 2004-09-22 | — | — | EP | disclosed |
| US-6593312-B2 | Hypoglycemic agents; antidiabetic agents; dietetics | LES LABORATOIRES SERVIER (FR) | 2003-07-15 | — | — | US | disclosed |
| US-20030004138-A1 | Cyclic a-amino-y hydroxyamide compounds | LES LABORATOIRES SERVIER (FR) | 2003-01-02 | — | — | US | disclosed |
| EP-1270562-A2 | Cyclic alpha-amino-gamma-hydroxy-amides, process for their preparation and pharmaceutical compositions thereof | Les Laboratoires Servier (FR) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004138-A1 | Cyclic a-amino-y hydroxyamide compounds | GPR119, SLC5A1, SLC5A2 | DPP4 609/4885DPP7 1821/4885PREP 2240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.