Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | IL6ST | P40189 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.36 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.36 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.36 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.36 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.36 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.36 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.36 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668597 | 1.00 | PPARA (0.44) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL6668336 | 1.00 | PPARA (0.44) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL8811308 | 0.94 | PPARA (0.46) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL8887105 | 0.94 | PPARA (0.46) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL132735 | 0.93 | PPARA (0.47) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL132736 | 0.93 | PPARA (0.47) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL6069116 | 0.92 | PPARA (0.43) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL6068526 | 0.92 | PPARA (0.43) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL6068528 | 0.92 | PPARA (0.43) | PPARAIL6STFAAHSLC1A1NAAA | |
| SCHEMBL16898532 | 0.91 | FAAH (0.40) | PPARAIL6STFAAHSLC1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-B1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PF MEDICAMENT (FR) | 2004-09-15 | — | — | EP | disclosed |
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |