Caprolactam

Caprolactam

SCHEMBL6668448

CCCCCC.O=C1CCCCCN1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.67
FKBP5 Q13451 1/20 0.67
OR51E2 Q9H255 1/20 0.56
ALOX5 P09917 2/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 1/20 0.43
POLB P06746 1/20 0.43
CCR2 P41597 6/20 0.39
SIRT2 Q8IXJ6 3/20 0.38
SIRT1 Q96EB6 3/20 0.38
SIRT3 Q9NTG7 3/20 0.38
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CXCR4 P61073 1/20 0.35
FAAH O00519 1/20 0.35
NAAA Q02083 1/20 0.35
CTSD P07339 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Undecane SCHEMBL3414259 0.98 CRBN (0.64) CRBNFKBP5OR51E2ALOX5KDM4E
Dodecane SCHEMBL27688625 0.98 CRBN (0.64) CRBNFKBP5OR51E2ALOX5KDM4E
Dodecane SCHEMBL28204455 0.96 CRBN (0.67) CRBNFKBP5OR51E2ALOX5KDM4E
Caprolactam SCHEMBL28288208 0.94 CRBN (0.59) CRBNFKBP5OR51E2ALOX5KDM4E
Caprolactam SCHEMBL29165574 0.94 CRBN (0.59) CRBNFKBP5OR51E2ALOX5KDM4E
Octane SCHEMBL28288276 0.93 FKBP5 (0.57) CRBNFKBP5OR51E2ALOX5KDM4E
Caprolactam SCHEMBL28289632 0.93 FKBP5 (0.57) CRBNFKBP5OR51E2ALOX5KDM4E
Caprolactam SCHEMBL28286059 0.91 CRBN (0.73) CRBNFKBP5OR51E2ALOX5KDM4E
Hexane SCHEMBL6861569 0.91 OR51E2 (0.68) CRBNFKBP5OR51E2ALOX5KDM4E
Tetrabuthylammonium SCHEMBL27764909 0.91 FKBP5 (0.55) CRBNFKBP5OR51E2ALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453884-A1 POLYMERIC NANOCOMPOSITE Quadrant IP AG (CH) 2004-09-08 EP disclosed
WO-2003033567-A1 POLYMERIC NANOCOMPOSITE RAG AKTIENGESELLSCHAFT (DE) 2003-04-24 WO disclosed